An Exchange between Free Purines and Pyrimidines and the Aglucones of Deoxyribosyl Purines and Deoxyribosyl Pyrimidines

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Nucleotide Metabolism – Purines and Pyrimidines

Nucleotide metabolism results in the synthesis of the four nucleotides that form DNA. These are further divided in two categories: purines and pyrimidines. Their construction and degradation takes place in a progression of single steps, while different enzymes and cofactors are involved in the process. Beside degradation, there is also a form of reprocessing purine and pyrimidine nucleotides, d...

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Nucleotide Metabolism – Purines and Pyrimidines

Nucleotide metabolism results in the synthesis of the four nucleotides that form DNA. These are further divided in two categories: purines and pyrimidines. Their construction and degradation takes place in a progression of single steps, while different enzymes and cofactors are involved in the process. Beside degradation, there is also a form of reprocessing purine and pyrimidine nucleotides, d...

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Nucleotide Metabolism – Purines and Pyrimidines

Nucleotide metabolism results in the synthesis of the four nucleotides that form DNA. These are further divided in two categories: purines and pyrimidines. Their construction and degradation takes place in a progression of single steps, while different enzymes and cofactors are involved in the process. Beside degradation, there is also a form of reprocessing purine and pyrimidine nucleotides, d...

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Endothelium-derived vasoconstriction by purines and pyrimidines.

The article by Tölle et al1 claims to show for the first time that adenosine 5 -tetraphosphate (AP4) is released on mechanical stimulation from human microvascular endothelial cells in the perfused rat kidney and, further, that AP4 is the most potent mediator of vascular smooth muscle constriction via P2X1 receptors or, indeed, via noradrenaline. It is well established that ATP and UTP released...

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ژورنال

عنوان ژورنال: Nature

سال: 1950

ISSN: 0028-0836,1476-4687

DOI: 10.1038/166444a0